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Stock Crash: Cancer drug developer shares plunge 48% after patient dies


Shares of Erasca Inc., a cancer-drug developer, fell as much as 55% in a single trading session on Tuesday, April 28, after the company informed that one of the patients enrolled in its clinical trial withdrew from treatment and later died after suffering severe side effects related to the treatment.

The stock eventually closed the session with losses of 48%.

A 66-year old man, who had enrolled for the trial, went to the emergency room with a severe lung inflammation, a month after beginning the company’s therapy. He later died after discontinuing treatment.
Based out of San Diego, Erasca disclosed data from an early-stage trial of its experimental therapy for pancreatic and lung cancer. Data showed that the treatment was generally well-tolerated with mostly low-grade side effects.
Tuesday’s fall was the biggest on record for shares of Erasca, since its public debut in 2021.

“While likely an isolated case in a complex patient, it introduces tension with the otherwise benign safety narrative and raises questions around attribution and reporting consistency,” HC Wainwright analyst Andres Y. Maldonado wrote in a note to clients.

Erasca’s 48% fall comes on the heels of another 11% decline on Tuesday, after the company received a cease-and-desist letter from rival Revolution Medicines Inc., which alleged that its cancer therapy is “substantially equivalent” to certain compositions claimed in a RevMed patent.

The fall in Erasca after its disclosure boosted fortunes of its rival RevMed, which surged 10%. The stock is up nearly 60% in the last one month after posting results of a late-stage trial earlier this month, which stated that its treatment for an aggressive form of pancreatic cancer boosted patients’ survival chances.

(With Inputs From Agencies)



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